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CDK inhibition

Showing 1 - 25 of 2,996
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Breast Cancer, Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Cancer Trial in Fairfax (Drug determined by

Recruiting
  • Breast Cancer
  • +2 more
  • Drug determined by treating oncologist based on recommendation from systems biology analysis.
  • Fairfax, Virginia
    Inova Schar Cancer Institute
Oct 13, 2021

Inhibition of Autophagy Synergizes Anti-tumor Effect Trial in Guangzhou (100mg bid dose of hydroxychloroquine combined with

Recruiting
  • Inhibition of Autophagy Synergizes Anti-tumor Effect
  • 100mg bid dose of hydroxychloroquine combined with three predefined dose groups of palbociclib
  • RP2D dose of 100mg bid of hydroxychloroquine combined with palbociclib was selected for phase II clinical trial.
  • Guangzhou, Guangdong, China
    Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Jul 19, 2023

COVID-19 Trial in Brandenburg an der Havel (Palbociclib)

Withdrawn
  • COVID-19
  • Brandenburg an der Havel, Germany
    Universitätsklinikum Brandenburg an der Havel
Nov 3, 2022

Chordoma Trial in Essen, Heidelberg, Ulm (Palbociclib)

Recruiting
  • Chordoma
  • Essen, Germany
  • +2 more
Dec 6, 2021

Breast Cancer Trial in Amsterdam, Groningen (FES-PET scan, and possibly one additional visit for an FDG-PET)

Recruiting
  • Breast Cancer
  • FES-PET scan, and possibly one additional visit for an FDG-PET
  • Amsterdam, Netherlands
  • +1 more
Jan 11, 2022

Associated With First-Line CDK4/6 Inhibition and Hormonal

Not yet recruiting
  • Metastatic Breast Cancer
  • Palbociclib + aromatase inhibitor
  • Aromatase inhibitor
  • New York, New York
    Pfizer
Sep 7, 2021

Anatomic Stage IV Breast Cancer AJCC v8, Hormone Receptor Positive Breast Carcinoma, Metastatic Breast Carcinoma Trial in Duarte

Recruiting
  • Anatomic Stage IV Breast Cancer AJCC v8
  • +3 more
  • Duarte, California
    City of Hope Medical Center
Nov 1, 2022

Breast Tumor Female Trial in Netherlands (CDK 4/6 inhibitor, Non-Steroidal Aromatase Inhibitor, Fulvestrant)

Active, not recruiting
  • Breast Neoplasm Female
  • CDK 4/6 inhibitor
  • +2 more
  • Alkmaar, Netherlands
  • +71 more
Apr 1, 2022

Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8 Trial in San

Recruiting
  • Castration-Resistant Prostate Carcinoma
  • +6 more
  • San Francisco, California
    University of California, San Francisco
Sep 8, 2022

Metastatic Breast Cancer, Breast Carcinoma Trial in United States (LEE-011, Fulvestrant, Placebo)

Active, not recruiting
  • Metastatic Breast Cancer
  • Breast Carcinoma
  • Birmingham, Alabama
  • +12 more
Feb 17, 2022

Metastatic Breast Cancer, ER+ Breast Cancer, Advanced Breast Cancer Trial in United Kingdom (Ipatasertib 300mg, Fulvestrant

Not yet recruiting
  • Metastatic Breast Cancer
  • +2 more
  • Ipatasertib 300mg
  • +3 more
  • Cambridge, Cambridgeshire, United Kingdom
  • +19 more
Jun 3, 2021

Metastatic Breast Cancer, Breast Cancer Stage IV Trial in São Paulo

Recruiting
  • Metastatic Breast Cancer
  • Breast Cancer Stage IV
    • São Paulo, SP, Brazil
      Hcor
    Sep 26, 2022

    Neurofibromatosis 1 Trial run by the National Cancer Institute (NCI) (Abemaciclib)

    Recruiting
    • Neurofibromatosis 1
    • Bethesda, Maryland
      National Institutes of Health Clinical Center
    Jan 20, 2023

    Metastatic Breast Cancer Trial in Al Madinah (Palbociclib)

    Not yet recruiting
    • Metastatic Breast Cancer
    • Al Madīnah, AL, Saudi Arabia
      Asmaa Imam Ahmed
    Oct 8, 2023

    Chondrosarcoma, Osteosarcoma, Soft Tissue Sarcoma Trial in United States (Abemaciclib)

    Recruiting
    • Chondrosarcoma
    • +2 more
    • Jacksonville, Florida
    • +3 more
    Apr 4, 2022

    Glioma Trial run by the National Cancer Institute (NCI) (pre-operative abemaciclib, Device for Cerebral Fluid Dialysate

    Recruiting
    • Glioma
    • pre-operative abemaciclib
    • +3 more
    • Bethesda, Maryland
      National Institutes of Health Clinical Center
    Feb 2, 2023

    Breast Cancer, Estrogen Receptor Positive Tumor, HER2-positive Breast Cancer Trial in Worldwide (Paclitaxel, Trastuzumab,

    Active, not recruiting
    • Breast Cancer
    • +2 more
    • Brasschaat, Belgium
    • +53 more
    Nov 29, 2022

    Sarcoma Trial in Guangzhou (Fluzoparib+ Dalpiciclib)

    Recruiting
    • Sarcoma
    • Fluzoparib+ Dalpiciclib
    • Guangzhou, Guangdong, China
      Cancer Center of Sun-Yat Sen University (CCSYSU)
    Jul 11, 2023

    Breast Cancer Trial in Marseille (M1774, Fulvestrant injection)

    Not yet recruiting
    • Breast Cancer
    • Marseille, France
      Institut Paoli Calmettes
    Aug 9, 2023

    Prostate Cancer, Prostatic Cancer, Cancer of Prostate Trial (NUV-422, Enzalutamide)

    Not yet recruiting
    • Prostate Cancer
    • +7 more
    • (no location specified)
    Jan 12, 2022

    Advanced Breast Cancer, Metastatic Breast Cancer, Breast Cancer Trial in United States (NUV-422, Fulvestrant)

    Recruiting
    • Advanced Breast Cancer
    • +7 more
    • Anaheim, California
    • +4 more
    Apr 6, 2022

    NHL, Adult, AML, Adult Recurrent Trial in Zhengzhou, Tianjin (ETH-155008)

    Recruiting
    • NHL, Adult
    • AML, Adult Recurrent
    • Zhengzhou, Henan, China
    • +1 more
    Feb 24, 2023

    Metastatic Breast Cancer, Recurrent Ovarian Carcinoma Trial in Salt Lake City, Fairfax (Ribociclib, Belinostat)

    Recruiting
    • Metastatic Breast Cancer
    • Recurrent Ovarian Carcinoma
    • Salt Lake City, Utah
    • +1 more
    May 3, 2022

    Mesothelioma, Uveal Melanoma, Renal Cell Carcinoma Trial in Gainesville, Miami, Orlando (Niraparib)

    Completed
    • Mesothelioma
    • +3 more
    • Gainesville, Florida
    • +2 more
    Jan 4, 2023

    Neuroblastoma, Cancer Trial in Philadelphia (procedure, genetic, other, behavioral, drug)

    Terminated
    • Neuroblastoma
    • Cancer
    • Biopsy
    • +12 more
    • Philadelphia, Pennsylvania
      The Children's Hospital of Philadelphia
    Jan 31, 2023